These particular compounds that are found in foods which have been consumed for hundreds of years have been shown to have incredibly potent – and selective - beta 2-adrenoceptor agonist properties in vitro...
In fact, their potency in terms of increasing cAMP is greater than that of salbutamol and rivals that of the clenbuterol, often used to, "harden", the physique by increasing muscle and decreasing fat mass (1).
It is believed to do so by activating the same signaling pathway that the powerful anabolic hormones, insulin and IGF-1, are able to activate...
In short, coumaroyldopamine & caffeoyldopamine have demonstrated the ability in vitro to increase cAMP and in turn activate Akt signaling…
Furthermore, these incredible compounds may also be able to increase muscle mass by cAMP and non-cAMP mediated mechanism (also involving Akt activation) which ultimately result in increased activation of mammalian target of rapamycin (mTOR) signaling (2,3).
Yet, another mechanism is by potentially modifying polyamine levels (androgens and GH are thought to potentially increase muscle hypertrophy by doing this), it can create yet another mechanism enabling muscle growth (5).
So, the compounds are able to activate pathways involved in the inhibition of skeletal muscle atrophy, while also being able to activate pathways involved in skeletal muscle hypertrophy. In short, it can potentially prevent muscle from being broken down, while also increasing muscle size.
If this weren't enough, by also increasing cAMP in fat tissue, Hormone Sensitive Lipase (HSL), which stimulates lipolysis, can be activated and lead to a reduction of fat mass.
Symplocos Racemosa Extract (standardized for triterpenoids)
This very specific extract was designed to maximize the levels of compounds which can have an additive or even synergistic effect with coumaroyldopamine & caffeoyldopamine by further enhancing their cAMP-increasing effects. It does this in part by inhibiting the degradation of cAMP...
It also goes without saying that this in turn enhances the anti-catabolic/anabolic and lipolytic effects of the coumaroyldopamine & caffeoyldopamine.
In addition, extraction for specific triterpenoid compounds is also expected to further enhance the potential ability of the formulation to increase muscle mass and decrease fat mass by enhancing skeletal muscle insulin/IGF-1 signaling, as was shown with similar compounds in animal models and in vitro (4).
Clinical studies are pending to evaluate Compound 20 and its effects upon body composition.
Incredible by itself, complete game changer when stacked with thermo's or anabolics...
WARNING: Don't expect to be "stimmed" from Compound 20
When's The Last Time You Looked In The Mirror And Said "I'd Like To Lose My Muscle And Gain Some Fat!"
Umm, that would be never and exactly why you need to get on Compound 20 NOW with its wide variety of stack applications:
Lean Bulk – This is the most obvious as this user is already tailoring his diet, training & supplementation to "gain lean mass & get ripped".
Cutting – Anyone who begins cutting would give just about anything to keep their muscle while shredding up. Imagine being pumped all day on a low carbohydrate diet!
Serving Size: 2 Capsules
Servings Per Container: 60
Each serving of USP Labs Compound 20 contains:
Proprietary Blend 1520 mg
[Symplocos Racemosa Extract (Bark)(Standardized for Triterpenoids), N-Coumaroyldopamine, N-Caffeoyldopamine]
USP Labs Compound 20 Directions:
As a dietary supplement take 2 capsules with breakfast and 2 capsules 6-8 hours later with meal or snack. For best results, take one of the doses 30-60 minutes prior to workout.
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